
Paula's Choice
Barrier Repair Advanced Moisturizer
50ml
Moisturiser step from Paula's Choice · Everyday routine staple

55ml
A lightweight pink capsule-textured moisturiser built around salmon-derived PDRN, collagen and niacinamide. Aimed at everyday hydration with a soft glow finish rather than a rich occlusive feel.
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Compare ingredients, suitability and claims side by side — pick your own, or let us line up the closest alternatives.
What's doing the work
Niacinamide
A form of vitamin B3 that supports the skin barrier and helps regulate oil.
Excess oil · Uneven tone · Texture · Redness
PDRN
PDRN stands for polydeoxyribonucleotide — short fragments of DNA, most often derived from salmon, used in skincare as a hydrating, soothing and barrier-supporting active. In topical formulas it is generally positioned as a "skin-conditioning" ingredient aimed at comfort, plumpness and a smoother look.
Dehydration · Redness · Fine lines · Texture · post-procedure-comfort
Alternatives

Paula's Choice
50ml
Moisturiser step from Paula's Choice · Everyday routine staple

Avène
100ml
Moisturiser step from Avène · Key actives: centella

La Roche-Posay
100ml
Moisturiser step from La Roche-Posay · Key actives: centella, panthenol

Paula's Choice
60ml
Moisturiser step from Paula's Choice · Everyday routine staple